Bios Archive - Page 7 of 11 - Connecticut Academy of Science and Engineering

Roy S. Herbst

Ensign Professor Of Medical Oncology And Pharmacology, Yale School Of Medicine

Elected to the Academy in 2025

Education

Yale University, 1984, BS, MS, Molecular Biophysics & Biochemistry 1984; Rockefeller University, 1990, PhD, Molecular Cell Biology; Cornell University Medical College, 1991, MD; Harvard University, 1997, MS, Clinical Translational Research

Professional Areas

Physician scientist leader in the development of targeted and immune therapies of non-small cell lung cancer and an innovator of master protocols (beginning with the BATTLE trial and leading to the Lung MAP Master protocol) and pragmatic clinical trial designs that identify novel molecular targeting agents.

Citation

Pioneer in the development of targeted and immune-based therapies for lung cancer, revolutionizing disease treatment through master protocols and pragmatic clinical trial designs based on patient biomarkers and personalized medicine; advanced standard of care, improved patient outcomes, and enhanced clinical trial diversity.

Jie He

Professor Of Chemistry, UConn College Of Liberal Arts And Sciences

Elected to the Academy in 2025

Education

Sichuan University (China), 2005, BS, Polymer Science and Engineering, 2008, MS, Polymer Material Science and Engineering; Université de Sherbrook (Canada), 2010, PhD, Chemistry

Professional Areas

Materials chemistry including polymers and nanomaterials; physical chemistry; surface chemistry; heterogeneous catalysis; artificial enzymes; CO2 reduction

Citation

For contribution on synthetic materials chemistry to advance the rational design of polymer/inorganic hybrids, including development of new polymer ligand chemistry on metal nanoparticles, microenvironment control on catalytic metal ions/nanoparticles, synthesis of crystalline, porous metals and oxides using hybrid polymers.

Guozhen Lu

Professor Of Mathematics, Uconn College Of Liberal Arts And Sciences

Elected to the Academy in 2025

Education

Zhejiang University, 1983, BS, Mathematics; Rutgers University, 1991, PhD

Professional Areas

Harmonic and Fourier analysis on Euclidean space, Heisenberg groups and Helgason-Fourier analysis on hyperbolic and symmetric spaces, geometric and functional inequalities and their stabilities, multi-parameter harmonic analysis and Hardy spaces, partial differential equations, analysis on Riemannain manifolds.

Citation

For outstanding contributions to harmonic analysis, partial differential equations and geometric analysis, in particular for developing innovative methods of studying sharp geometric and functional inequalities using Helgason-Fourier analysis on hyperbolic and symmetric spaces, and contributions to sharp geometric inequalities and their stabilities, and multi-parameter harmonic analysis.

Charles A. Greer

Professor Of Neurosurgery And Neuroscience, Yale School Of Medicine

Elected to the Academy in 2025

Education

University of Colorado, 1971, BA, English/Psychology; 1976, MA, Neuroscience; 1978, PhD, Neuroscience

Professional Areas

Pioneer in understanding the development and organization of the olfactory bulb, the brain region that enables us to smell. Led Yale’s esteemed Interdepartmental Neuroscience Program for 25 years as its director.

Citation

For major contributions to our understanding of the development and function of the olfactory system, including the cellular and organization of the olfactory bulb. For leading graduate neuroscience education at Yale, training several generations of world-leading neuroscientists.

Gene M. Dubowchik

Senior Vice President, Molecular Technologies, Biohaven Pharmaceuticals

Elected to the Academy in 2025

Education

Franklin and Marshall College, 1981, AB, Chemistry & History; Princeton University, 1983, MA, Chemistry; Princeton University, 1987, PhD, Chemistry

Professional Areas

Small molecule medicinal chemistry, primarily in the areas of neuroscience, oncology, and immunology, biologics drug discovery, especially in the Areas of antibody drug conjugates (ADCs) for oncology and immunological disease, and extracellular degraders – both small molecule and protein-based.

Citation

For seminal contributions to antibody-drug conjugate (ADC) linker design that is represented in five marketed Oncology ADC drugs and his role as a co-inventor of two FDA approved CNS migraine drugs Nurtec® (rimegepant) and Zavzpret® (zavegepant), conferring international stature, reputation and visibility in the medicinal chemistry community.

Sabrina Diano

Robert R. Williams Professor Of Nutrition & Director Of The Insttute Of Human Nutrition, Columbia University Medical Center; Adjunct Professor Of Cellular & Molecular Physiology, Yale School Of Medicine

Elected to the Academy in 2025

Education

University of Naples “Federico II”, (Italy), 1999, PhD

Professional Areas

Neurobiology of metabolism research has important implications for understanding the pathogenesis of metabolic disorders such as obesity and type 2 diabetes, the leading cause of morbidity and mortality in the US and the developed world in general, with the highest financial burden on nations’ economy.

Citation

Provided fundamental novel insights into hypothalamic regulation of metabolism, establishing a key role for mitochondria metabolism and dynamics in nutrient-sensing mechanisms that enable brain cells to regulate energy and glucose metabolism; Directs the Institute of Human Nutrition at Columbia University, awarding Master and PhD degrees, thus providing an important platform to advance science.

Keith A. Choate

Aaron B. And Marguerite Lerner Professor And Chair Of Dermatology, Yale School Of Medicine

Elected to the Academy in 2025

Education

Stanford University, 1995, BS, Biological Sciences; Yale University School of Medicine, 2000, MPhil, Cell Biology; 2001, PhD, Cell Biology; 2004, MD

Professional Areas

The genetics and pathophysiology of human diseases of the skin (dermatology).

Citation

For seminal discoveries in the genetics of inherited and somatic mosaic skin disorders, revealing central contributors to epidermal barrier function, cell fate specification, and neoplasia. Work has led to novel therapeutics actively employed in clinical practice in rare and common genetic skin diseases.

Ming-Hui Chen

Statistics Department Head And Board Of Trustees Distinguished Professor, UConn College Of Liberal Arts And Sciences

Elected to the Academy in 2025

Education

Hangzhou University (China), 1983, BS, Mathematics; Shanghai Jiao Tong University (China), 1985, MS, Applied Mathematics; Purdue University, 1991 MS, Statistics; 1993, PhD, Statistics

Professional Areas

Bayesian Statistical Methodology, Bayesian Computation, Bayesian Phylogenetics, Categorical Data Analysis, Design of Bayesian Clinical Trials, DNA Microarray Data Analysis, Meta-analysis (http://merlot.stat.uconn.edu/packages/metapack/), Missing Data Analysis (EM, MCEM, and Bayesian), Monte Carlo Methodology, Prior Elicitation, Statistical Methodology and Analysis for Prostate Cancer Data, Statistical Modeling, Survival Data Analysis, and Variable Selection.

Citation

For outstanding research contributions in Statistics, Biostatistics, and medical research; outstanding performance in teaching, consulting, mentoring at UConn; and service to UConn and outreach at the state, national and international level.

Iuliana Cernatescu

Senior Technical Fellow, Materials Characterization And Applications; Pratt & Whitney

Elected to the Academy in 2025

Education

Instituto Balseiro (Argentina), 1990, BS/MS, Nuclear Engineering; 1993, PhD, Nuclear Engineering

Professional Areas

Expert in materials characterization, conducting advanced research and application efforts through collaborations with national laboratories, universities, and designing and building one of the most state-of-the-art industrial materials characterization labs. She is an expert in the physics of materials characterization and industrial applications engineering.

Citation

For numerous contributions to naval hydrodynamics, advancement of computational tools and mathematical models to simulate flows around ships; development of models and numerical algorithms for the solution of free surface flows, bubbly flows, cavitation inception and bubble entrainment; development of techniques to enable simulation of ship motions and control.

Pablo M. Carrica

Principal Engineer, Department Of Fluid Mechanics; General Dynamics Electric Boat

Elected to the Academy in 2025

Education

Instituto Balseiro (Argentina), 1990, BS/MS, Nuclear Engineering; 1993, PhD, Nuclear Engineering

Professional Areas

Fluid mechanics, naval hydrodynamics, multiphase flows, computational fluid dynamics, cavitation.

Citation

For numerous contributions to naval hydrodynamics, advancement of computational tools and mathematical models to simulate flows around ships; development of models and numerical algorithms for the solution of free surface flows, bubbly flows, cavitation inception and bubble entrainment; development of techniques to enable simulation of ship motions and control.