Education
University of Vienna, 1998, Diploma Magister, Chemistry; University of Frankfurt, 2001, PhD, Chemistry
Professional Area(s)
Molecular analysis of complex signaling events; Protein Phosphatases and Kinases in eukaryotic signaling; substrate specificity for protein phosphatases; structural biology; NMR, X-ray; cryo-EM; bacterial antibiotic resistance; penicillin-binding proteins, X-ray crystallography based screening and small molecule drug design
Citation
For seminal contributions to the analysis of mechanisms of enzyme function, including the high specificity of Ser/Thr protein phosphatases via complex formation with regulatory proteins, how SerThr protein kinases’ activity is modulated by protein dynamics, and new insight into drug resistance of bacterial penicillin-binding proteins.