Yale School of Medicine
Education
Fujian Medical University (Fuzhou, China), 1982, MD; Beijing Union Medical College (Beijing, China), 1986, MSc, Microbiology & Immunology; Drexel University College of Medicine, 1989, PhD, Pathology
Professional Area
Immunologist and research oncologist with interests in understanding how to control and modulate immune responses to fight cancer as well as autoimmune and inflammatory diseases.
Citation
Pioneer in the field of cancer immunotherapy, including fundamental research that led to the cloning of B7-H1(PD-L1), subsequent demonstration of the immunosuppressive functions of the B7-H1/PD-1 signaling pathway; use of antibody blockade of this pathway as a cancer immunotherapy; pivotal discovery of costimulation as a mechanism to improve tumor immunity, leading to the development of breakthrough treatments for human cancer.