José Manuel Otero
José Manuel Otero
Chief Technology Officer and Executive Team Member, Turnstone Biologics
Elected to the Academy in 2020


Massachusetts Institute of Technology, 2001, BS, Chemical Engineering and 2002, MS, Biomedical Engineering, Massachusetts Institute of Technology; Chalmers University of Technology, 2009, PhD, Biological and Chemical Engineering

Professional Area

Deep expertise in bioprocess development of advanced biopharmaceutical therapeutics, spanning all aspects of Drug Substance and Product across clinical and commercial GMP manufacturing. This includes special focus on all aspects of CMC development for microbial-based manufacturing for vaccines/microbiome therapeutics, and live-virus vaccine manufacturing.


For engineering excellence in disruptive human therapeutics discovery and development and tackling global unmet human health needs. This has included contributing to the development of the first transformative HPV vaccine, enabling clinical study of the first human microbiome therapeutic, and developing next-generation viral immunotherapies for cancer.